首页>
外国专利>
Mutant polyhydroxyalkanoate synthase, gene thereof and transformant, and method for producing polyhydroxyalkanoate
Mutant polyhydroxyalkanoate synthase, gene thereof and transformant, and method for producing polyhydroxyalkanoate
展开▼
机译:突变体多羟基烷酸盐合酶,其基因和转化体,以及生产多羟基烷烷的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
Provided is a mutant PHA synthase which produces of a PHA copolymer with a high or low 3HH ratio while maintaining PHA productivity. The mutant PHA synthase is a mutant polyhydroxyalkanoate synthase having an amino acid sequence having 85% or more sequence identity with the amino acid sequence of SEQ ID NO: 1 and having at least one of the following mutations (a) to (c): (a) a substitution of serine at 389th position from N-terminus of the amino acid sequence of SEQ ID NO: 1 with an amino acid other than serine; (b) a substitution of leucine at 436th position from the N-terminus of the amino acid sequence of SEQ ID NO: 1 with an amino acid other than leucine; and (c) a deletion of 11 to 19 amino acid residues from the C-terminus of the amino acid sequence of SEQ ID NO: 1.
展开▼
机译:提供的是突变体PHA合酶,其在保持PHA生产率的同时产生高或低3HH比的PHA共聚物。 突变体PHA合酶是突变聚羟基烷酸合酶合成酶,其具有85%或更多序列同一性的氨基酸序列,SEQ ID NO:1的氨基酸序列并具有以下突变(a)至(c)中的至少一种:( a)从SEQ ID NO:1的氨基酸序列的N-末端的第389位取代丝氨酸,其与丝氨酸以外的氨基酸; (b)从SEQ ID NO:1的氨基酸序列的N-末端用氨基酸的N-末端取代亮氨酸,除亮氨酸以外的氨基酸; (c)从SEQ ID NO:1的氨基酸序列的C-末端删除11至19个氨基酸残基。
展开▼