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Precision treatment with machine learning and digital twin technology for optimal metabolic outcomes

机译:具有机器学习和数字双胞胎技术的精密处理,实现最佳代谢结果

摘要

A patient health management platform accesses a metabolic profile for a patient and biosignals recorded for the patient during a current time period comprising sensor data and/or lab test data collected for the patient. The platform encodes the biosignals into a vector representation and inputs the vector representation into a patient-specific metabolic model to determine a metabolic state of the patient at a conclusion of the current time period. The patient-specific metabolic model comprises a set of parameter values determined based on labels assigned to the previous metabolic states and a function representing one or more effects of the plurality of biosignals of the personalized metabolic profile. The platform compares the determined metabolic state of the patient to a threshold metabolic state representing a target metabolism. The platform generates a patient-specific treatment recommendation outlining instructions for the patient to improve the determined metabolic state to the functional metabolic state.
机译:患者健康管理平台在包括用于患者收集的传感器数据和/或实验室测试数据的当前时间段期间,用于为患者记录为患者的患者和生物信号的代谢型材。该平台将生物形象编码为向量表示,并将向量表示输入到患者特异性代谢模型中,以确定当前时间段的结论中患者的代谢状态。患者特定的代谢模型包括基于分配给先前代谢状态的标签和表示个性化代谢型材的多个生物信号的一个或多个效果的函数确定的一组参数值。该平台将患者的确定代谢状态与表示靶代谢的阈值代谢状态进行比较。该平台产生患者的特定患者的治疗建议,概述患者的指示,以改善确定的代谢状态与功能性代谢状态。

著录项

  • 公开/公告号US11185283B2

    专利类型

  • 公开/公告日2021-11-30

    原文格式PDF

  • 申请/专利权人 TWIN HEALTH INC.;

    申请/专利号US202117202353

  • 申请日2021-03-16

  • 分类号G16H40/67;A61B5;G16H15;A61B5/11;A61B5/145;G16H50/30;G16H20/10;G16H20/60;G16H50/20;G16H10/40;G16H50/50;G16H10/60;G06N20;A61B5/0205;

  • 国家 US

  • 入库时间 2022-08-24 22:13:57

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