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Viscoelastic analysis in patients with disease associated with cardiovascular system

机译:心血管系统疾病患者的粘弹性分析

摘要

In some embodiments, the invention provides a method for identifying a patient suffering from or suspected of suffering in from a disease associated with the cardiovascular system that is having a subnormal response to the treatment for the disease comprising: subjecting a blood sample from a patient being treated for a disease to a viscoelastic analysis in the presence of a known amount of a thrombolytic agent, to obtain a coagulation characteristic value of the patient; and comparing the coagulation characteristic value of the patient to a coagulation characteristic value of a healthy individual, wherein a difference in the coagulation characteristic value of the patient as compared to the coagulation characteristic value of the healthy individual identifies the patient as a patient having a subnormal response to treatment.
机译:在一些实施方案中,本发明提供了一种鉴定患有或可疑来自与心血管系统相关的疾病中患有患者的患者的方法,该患者具有对该疾病的治疗具有亚因响应的疾病:从患者进行患者进行血液样品 在已知量的血栓溶解剂存在下对粘弹性分析进行疾病治疗,得到患者的凝固特征值; 并将患者的凝血特征值与健康个体的凝固特征进行比较,其中与健康个体的凝血特征相比,患者的凝血特征值的差异将患者鉴定为具有亚型患者的患者 对治疗的反应。

著录项

  • 公开/公告号US11169142B2

    专利类型

  • 公开/公告日2021-11-09

    原文格式PDF

  • 申请/专利号US201716300491

  • 发明设计人 MICHAEL P. CHAPMAN;

    申请日2017-05-11

  • 分类号G01N33/49;G01N33/86;A61K31/4439;C12Q1/56;G01N33/48;A61F2/01;A61F2/82;A61M1/36;A61M25/10;G01N11/14;

  • 国家 US

  • 入库时间 2022-08-24 22:08:51

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