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MOLECULAR TECHNOLOGY FOR DETECTING A GENOME SEQUENCE IN A BACTERIAL GENOME

机译:用于检测细菌基因组中基因组序列的分子技术

摘要

A computer-implemented method for detecting a genome sequence in digital form in a genome of a microorganism in digital form, comprising: - storing (60), in a computer memory, a set of digital genome sequences of constant length k, or 'k-mers', the set being obtained by sliding, at a constant pitch, a window of length k over the genome sequence; - for each k-mer, determining (802) its absence or presence in the genome; - determining (806, 808) that the genome sequence is present in the genome if the percentage of k-mers detected as present in the genome is higher than a predetermined threshold.
机译:一种计算机实施方法,用于在数字形式的微生物的基因组中检测数字形式的基因组序列,包括: - 在计算机存储器中存储(60),一组恒定长度K的数字基因组序列,或'k - 使得通过在基因组序列的恒定间距下滑动,在恒定间距下滑动,在恒定间距下获得。 - 对于每种K-ME1,确定(802)其在基因组中的不存在或存在; - 确定(806,808)如果以基因组中存在的K-MER百分比高于预定阈值,则基因组序列存在于基因组中。

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