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OFF-TARGET CAPTURE REDUCTION IN SEQUENCING TECHNIQUES
OFF-TARGET CAPTURE REDUCTION IN SEQUENCING TECHNIQUES
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机译:排序技术的偏离目标捕获降低
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摘要
Presented herein are methods and compositions for enhancing specific enrichment of target sequences in a nucleic acid library. Off-target hybridization probes may be used to reduce binding and/or capture of off-target regions of a nucleic acid library in a targeted sequencing workflow. The off-target hybridization probes may be specific for locations known to generate off-target sequencing reads for a particular set of hybridization probes.
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