INFORMATION-ADAPTIVE REGULARIZATION FOR ITERATIVE IMAGE RECONSTRUCTION

摘要

Imaging data (20) are acquired by a PET scanner (6) or other imaging device. Iterative image reconstruction of the imaging data is performed to generate a reconstructed image (22). The iterative image reconstruction includes performing an update step (24) that includes an edge preserving prior (28) having a spatially varying edge preservation threshold (30) whose value at each image voxel depends on a noise metric (32) in a local neighborhood of the image voxel. The noise metric may be computed as an aggregation of the intensities of neighborhood image voxels of the reconstructed image in the local neighborhood of the image voxel. The edge preserving prior may be a Relative Difference Prior (RDP). For further noise suppression, during the iterative image reconstruction image values of image features of the reconstructed image that have spatial extent smaller than a threshold (38) may be reduced.