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Nanovesicles from kupreawidis bacteria and their use

机译:来自库普雷雷西的纳米粒子及其使用

摘要

The present invention relates to vesicles derived from a bacterium of the genus Cupriavidus and uses thereof. The present inventors compared with normal people, gastric cancer, colon cancer, pancreatic cancer, bile duct cancer, breast cancer, ovarian cancer, bladder cancer, prostate cancer, head and neck cancer, malignant diseases such as lymphoma, cardiomyopathy, atrial fibrillation, Heart vesicles such as variant angina, chronic obstructive pulmonary disease, stroke, diabetes, renal failure, dementia, Parkinson's disease and depression, the vesicles are significantly reduced, and the vesicles are pathogenic. It significantly suppressed the secretion of inflammatory mediators by sex vesicles and at the same time suppressed the development of cancer. Vesicles derived from cupriawidus bacterium according to the present invention, gastric cancer, colon cancer, pancreatic cancer, bile duct cancer, breast cancer, ovarian cancer, bladder cancer, prostate cancer, head and neck cancer, lymphoma and other malignant diseases, cardiomyopathy, Atrial fibrillation, heart disease such as variant angina, chronic obstructive pulmonary disease, stroke, diabetes, renal failure, dementia, Parkinson's disease or depression, and a method for preventing or treating the disease are developed. Useful for the purpose. [Selection diagram] None
机译:本发明涉及衍生自Cupriavidus属的细菌和其用途的囊泡。本发明人与正常人相比,胃癌,结肠癌,胰腺癌,胆管癌,乳腺癌,卵巢癌,膀胱癌,前列腺癌,头部和颈部癌,恶性疾病,如淋巴瘤,心肌病,心房颤动,心脏囊泡如变异性心绞痛,慢性阻塞性肺病,中风,糖尿病,肾衰竭,痴呆,帕金森病和抑郁,囊泡显着降低,囊泡是致病性的。它显着抑制了性囊泡的炎症介质的分泌,同时抑制了癌症的发展。根据本发明,胃癌,结肠癌,胰腺癌,胆汁导管,乳腺癌,卵巢癌,膀胱癌,前列腺癌,头部和颈癌,淋巴瘤和其他恶性疾病,心肌病,心肌病发育了肉质疾病,如变异性心绞痛,慢性阻塞性肺病,中风,糖尿病,肾衰竭,痴呆,帕金森病或抑郁症等心脏病,以及预防或治疗疾病的方法。对目的有用。 [选择图]无

著录项

  • 公开/公告号JP6959664B2

    专利类型

  • 公开/公告日2021-11-02

    原文格式PDF

  • 申请/专利号JP20190548319

  • 发明设计人 キム、ユン-クン;

    申请日2019-02-20

  • 分类号C12Q1/06;A61K35/74;A61P35;A61P9;A61P9/06;A61P11;A61P25/28;A61P3/10;A61P13/12;A61P25/16;A61P25/24;A23L33/135;C12Q1/689;C12N1/20;C12N15/11;G01N33/50;G01N33/53;

  • 国家 JP

  • 入库时间 2022-08-24 22:02:35

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