UV EXCITED MULTI SPECTRAL FLUORESCENCE BASED TISSUE ANALYSIS WITH RAMAN SPECTROSCOPY ZOOM-IN SCANNING

摘要

A method and system of analyzing a resected tissue specimen is provided. The method includes: a) using an imaging system to image a tissue sample with excitation light configured to produce fluorescent emissions from the tissue sample, the imaging producing signals representative of the fluorescent emissions from the sample; b) determining a presence or an absence of at least one suspect tissue region on the tissue sample; c) determining a spatial location of said at least one suspect tissue region determined to be present on the tissue sample; d) using the imaging system to image the suspect tissue region at the determined spatial location with excitation light configured to produce Raman scattering from the sample, the imaging producing signals representative of the Raman scattering from sample; and e) analyzing the determined suspect tissue region using the signals representative of the Raman scattering from the sample.