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PHARMACEUTICAL PRACTICE 3D PRESSURE

机译:药业实践3D压力

摘要

Provided herein are devices and systems for depositing a material or manufacturing a product, such as a pharmaceutical dosage form, by additive manufacturing. Further provided are methods of using the devices and systems, as well as methods of manufacturing a product, such as a pharmaceutical dosage form, by additive manufacturing. In certain embodiments, the device includes a material supply system configured to melt an pressurized a material, a pressure sensor configured to detect a pressure of the material within the device, and a control switch comprising a sealing needle operable in an open position and closed position. The sealing needle extends through a feed channel containing the material and includes a taper end, wherein the tapered end of the sealing needle engages a tapered inner surface of a nozzle to inhibit flow of the material through the nozzle when the sealing needle is in the closed position.
机译:本文提供了用于通过添加剂制造沉积材料或制造产品,例如药物剂型的产品和系统。 进一步提供了使用装置和系统的方法,以及通过添加剂制造制造产品,例如药物剂型的方法。 在某些实施例中,该装置包括材料供应系统,该材料供应系统被配置为熔化加压的材料,压力传感器被配置为检测装置内的材料的压力,以及包括在打开位置和关闭位置可操作的密封针的控制开关的控制开关 。 密封针延伸穿过包含材料的进料通道,并且包括锥形端,其中,密封针的锥形端部接合喷嘴的锥形内表面,以禁止当密封针处于关闭时通过喷嘴流过喷嘴的流动 位置。

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