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Combined automatic filtration of peptide crystal separation, washing and drying
Combined automatic filtration of peptide crystal separation, washing and drying
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机译:肽晶体分离,洗涤和干燥的组合自动过滤
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摘要
The present invention describes the integration of preparative crystallization, crystal separation, crystal washing and freeze-drying processes into single continuous process using pressure filtration. The process facilitates time reduction, and outlines the novel design of using multiple organic solvent washes and nitrogen gas purging for the removal of imbibed water and achieve final drug substance that meets the quality specifications.
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