DEVICE AND METHOD FOR PHOTOTHERMAL ENHANCED PLASMONIC BIOSENSING

摘要

The present invention is directed to a dual-functional plasmonic detector comprising (a) a photothermal unit configured to generate a monochromatic light beam; (b) a plasmonic sensing unit configured to introduce a localized surface plasmon resonance effect and to transduce a target sample by means of a polychromatic radiation beam; and (c) a detection unit configured to detect plasmonic characteristics by recording and processing the radiation beam altered by the plasmonic sensing unit. The invention also relates to the use of the dual-functional plasmonic detector of the invention for detecting, quantifying and/or characterizing a target sample, in particular for detecting, quantifying and/or characterizing a nucleic acid or a virus, e.g. a coronavirus such as SARS-CoV or SARS-CoV-2.