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CLINICALLY MEANINGFUL AND PERSONALIZED DISEASE PROGRESSION MONITORING INCORPORATING ESTABLISHED DISEASE STAGING DEFINITIONS

机译:临床有意义和个性化的疾病进展监测纳入既定的疾病分期定义

摘要

A non-transitory computer readable medium (26) stores instructions executable by at least one electronic processor (20) to perform a method (100) for staging a disease having a predefined ordered set of S discrete stages where S is an integer having a value greater than or equal to two. The method includes: for each discrete stage of the S discrete stages, defining a representative vector (30) for the discrete stage in a vector space defined by a set of clinical metrics based on a set of training patients labeled with the discrete stage and with values for the set of clinical metrics; for a patient to be staged, receiving patient values for the set of clinical metrics; generating at least one stage value for the patient to be staged based on distances in the vector space between a patient vector defined in the vector space by the patient values for the set of clinical metrics and the representative vectors for the S discrete stages in the vector space; and displaying the at least one stage value for the patient to be staged on a display device (24) operatively connected with the electronic processor.
机译:非暂时性计算机可读介质(26)存储由至少一个电子处理器(20)执行的指令,以执行用于分段具有预定义有序集的S离散阶段的疾病的方法(100),其中S是具有值的整数大于或等于两个。该方法包括:对于S离散阶段的每个离散阶段,在由一组临床指标基于一组培训患者标记为离散阶段的一组培训患者定义的用于离散阶段的代表性矢量(30)。临床指标集的价值观;对于患者进行分阶段,接受临床指标的患者值;产生患者的至少一个阶段值,该级值基于矢量空间中的距离在矢量空间中的距离由临床指标集的患者值和矢量的代表向量之间的患者值之间进行阶段的距离。空间;并在与电子处理器可操作地连接的显示装置(24)上,显示患者的至少一个级值。

著录项

  • 公开/公告号WO2021205033A1

    专利类型

  • 公开/公告日2021-10-14

    原文格式PDF

  • 申请/专利权人 KONINKLIJKE PHILIPS N.V.;

    申请/专利号WO2021EP59361

  • 发明设计人 ZHAO CLAIRE YUNZHU;

    申请日2021-04-10

  • 分类号G16H50/20;

  • 国家 EP

  • 入库时间 2022-08-24 21:43:25

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