COMPOSITION FOR CANCER PREVENTION OR TREATMENT, CONTAINING, AS ACTIVE INGREDIENT, SALVIANOLIC ACID B OR TANSHINONE I

摘要

The present invention relates to a composition for cancer prevention or treatment, containing, as an active ingredient, salvianolic acid B or tanshinone I. Specifically, provided are a pharmaceutical composition and a health functional food composition for KRAS-mutated cancer prevention or treatment, the compositions containing, as an active ingredient, salvianolic acid B or tanshinone I. Compared to a conventional therapeutic agent, salvianolic acid B or tanshinone I strongly binds to KRAS mutants so as to have an improved ability to target cancer cells induced by KRAS mutations, and thus diseases that are refractory to treatment with existing therapeutic agents, such as cancer in which KRAS mutations are overexpressed, can be effectively treated.