PHARMACEUTICAL COMPOSITIONS OF 6H-PYRIDO3,2-E1,2,4TRIAZOLO1,5-CPYRIMIDIN-5-ONE AND 1,2,4TRIAZOLO1,5-CPTERIDIN-5(6H)-ONE DERIVATIVES AS PDE1 INHIBITORS FOR TREATING E.G. NEUROLOGICAL DISORDERS

摘要

The present invention relates to 6-benzyl-6H-pyrido[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5-one and 6-benzyl-[1,2,4]triazolo[1,5-c]pteridin-5(6H)-one derivatives as phosphodiesterase 1 (PDE1) inhibitors for the treatment of e.g. neurological disorders, cognitive disorders, cardiovascular disorders, renal disorders and atherosclerosis.