A PHARMACEUTICAL COMPOSITION COMPRISING HYDROXYCHLOROQUINE, CHLOROQUINE, OR METABOLITE THEREOF

摘要

The present invention provides a pharmaceutical composition consisting of: a first pharmaceutically active portion consisting of hydroxychloroquine or a salt thereof and/or chloroquine or a salt thereof; a second pharmaceutically active portion consisting of one or more of glutathione, cysteine, acetylcysteine, alliin, bucillamine, carbocysteine, djenkolic acid, felinine, lanthionine, mecysteine hydrochloride, penicillamine cysteine disulphide, or any functional equivalent thereof; and optionally one or more excipients; wherein the molar ratio of the second pharmaceutically active portion to the first pharmaceutically active portion is at least 0.5:1. The present invention also provides a pharmaceutical composition consisting of: a first pharmaceutically active portion consisting of N-desethylhydroxy chloroquine and/or N-desethyl chloroquine or a salt thereof; and optionally one or more excipients.