首页> 外国专利> FUSION PROTEIN OF Z-DOMAIN AND CALSEQUESTRIN, HAVING IMPROVED REACTIVITY, STABILITY, AND ANTIBODY RECOVERY, AND METHOD FOR ISOLATION AND PURIFICATION OF ANTIBODY USING SAME

FUSION PROTEIN OF Z-DOMAIN AND CALSEQUESTRIN, HAVING IMPROVED REACTIVITY, STABILITY, AND ANTIBODY RECOVERY, AND METHOD FOR ISOLATION AND PURIFICATION OF ANTIBODY USING SAME

机译:Z-结构域和CALSECESTRIN的融合蛋白,具有改善的反应性,稳定性和抗体回收,以及用于使用相同抗体的分离和纯化的方法

摘要

The present invention relates to a fusion protein of the Z-domain and calsequestrin, having improved reactivity, stability, and antibody recovery, and a method for isolation and purification of an antibody using same. Specifically, the present invention relates to: a nucleic acid encoding a fusion protein of the Z-domain and calsequestrin having improved reactivity and stability; a recombinant expression vector comprising the nucleic acid; a transformant transformed with the recombinant expression vector; and a method for isolation and purification of an antibody with improved reactivity, stability, antibody recovery, and purity using the fusion protein of the Z-domain and calsequestrin.
机译:本发明涉及Z-结构域的融合蛋白和曲折,具有改善的反应性,稳定性和抗体回收,以及用于分离和纯化使用该抗体的方法。 具体地,本发明涉及:编码Z-结构域的融合蛋白的核酸和具有改善的反应性和稳定性的钙序列; 包含核酸的重组表达载体; 用重组表达载体转化的转化体; 以及使用Z-结构域的融合蛋白和钙序列的抗体,具有改善的反应性,稳定性,抗体回收和纯度的抗体的分离和纯化的方法。

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