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Method for producing a peptide compound, a reagent for forming a protecting group, and an aromatic heterocyclic compound

机译:制备肽化合物的方法,用于形成保护基的试剂,以及芳族杂环化合物

摘要

It relates to a method for producing a peptide compound comprising the step of using an aromatic heterocyclic compound represented by formula (1), a reagent for forming a protecting group containing the compound, and the compound. In formula (1), ring A represents an aromatic heterocycle, Y A each independently represents -OH, -NHR, -SH, or -X 0 , X 0 represents Cl, Br or I; R A and R C each independently represent an aliphatic hydrocarbon group or an organic group having an aliphatic hydrocarbon group, and R B are each independently a monovalent aliphatic hydrocarbon group, a (1+c) aromatic group or ( 1+c) represents a valent heteroaromatic group, and when both a and c are 0, R B is a monovalent aliphatic hydrocarbon group, and the number of carbon atoms in at least one of R A , R B and R C is 12 More than that.
机译:它涉及一种制备肽化合物的方法,包括使用由式(1)表示的芳族杂环化合物的步骤,用于形成含化合物的保护基的试剂和化合物。 在式(1)中,环A表示芳族杂环,ya独立地代表-OH,-NHR,-SH或-X 0,x 0代表Cl,Br或i; Ra和Rc各自独立地代表具有脂族烃基的脂族烃基或有机基团,并且Rb各自独立地为一价脂族烃基,(1℃)芳族基团或(1℃)代表价值杂芳族基团 当A和C都是0时,Rb是一价脂族烃基,并且Ra,Rb和Rc中的至少一种的碳原子数量比该为12。

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