METHODS FOR TARGETING, INHIBITING, AND TREATING A TUMORAL MICROENVIRONMENT

摘要

The present application relates to methods for targeting and/or inhibiting a tumoral microenvironment and/or tumor cells. More specifically, the present disclosure is directed to a method of targeting a tumor microenvironment of a subject, the method comprises, consists of, or consists essentially of inhibiting ST2* regulatory T cells present in the tumor microenvironment. The methods of the present disclosure further comprise blocking the IL-33/ST2 pathway.