SHIP1 SHIP1 MODULATORS AND METHODS RELATED THERETO

摘要

Described herein are compounds of Formula II: or a stereoisomer, enantiomer or tautomer thereof, or a mixture thereof, or a pharmaceutically acceptable salt or solvate thereof, as well as other compounds. Such compounds have activity as SHIP1 modulators and thus can be used to treat any of a variety of diseases, disorders or conditions that would benefit from SHIP1 modulation. Compositions comprising the compounds of the present invention are also disclosed, and methods of modulating SHIP1 by administering such compounds to an animal in need of modulation of SHIP1 are also disclosed. wherein A, R 1 , R 2 , R 5 and R 13 are described herein.