BIFUNCTIONAL PROTEINS COMBINING CHECKPOINT BLOCKADE FOR TARGETED THERAPY

摘要

FIELD: biotechnology.;SUBSTANCE: invention relates to a bispecific antibody for treating cancer, e.g., such as prostate cancer, lung cancer, NSCLC, melanoma, lymphoma, breast cancer, head and neck cancer, RCC, or ovarian cancer. The bispecific antibody comprises a binding domain binding a cell surface protein and a domain for inhibiting vascular endothelial growth factor (VEGF).;EFFECT: antibody applicable for treating different types of cancer.;16 cl, 16 dwg, 7 ex