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COMPOUND FOR TARGETED DEGRADATION OF FOCAL ADHESION KINASE AND MEDICAL APPLICATION THEREOF

机译:局灶性粘合激酶的靶向降解化合物及其医学应用

摘要

The present invention relates to a compound for targeted degradation of focal adhesion kinase and a medical application thereof. The present invention belongs to the technical field of medicines and provides a compound represented by general formula (I) or a geometric isomer, pharmaceutically acceptable salt, hydrate, solvate, or prodrug thereof and a preparation method therefor. The compound has good degradation activity on FAK kinase.
机译:本发明涉及局部粘附激酶靶向降解的化合物及其医学应用。 本发明属于药物技术领域,并提供通式(I)或几何异构体,药学上可接受的盐,水合物,溶剂化物或其前药的化合物及其制备方法。 该化合物对FAK激酶具有良好的降解活性。

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