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METHOD FOR DETERMINING FACTOR OF CHEMICAL SUBSTANCE INFLUENCING ENDOCRINE SYSTEM

机译:影响内分泌系统的化学物质系数的方法

摘要

The present invention provides a method for determining a factor of a chemical substance influencing the endocrine system in an organism, wherein the method includes (1) a step in which the expression amount of a gene serving as a marker and/or the amount of an endogenous metabolite serving as a marker in samples collected from a subject not brought into contact with the chemical substance and from a subject brought into contact with the chemical substance are measured, and (2) a step in which the expression amount of the gene and/or the amount of the endogenous metabolite measured in step (1) are subsequently analyzed and it is determined whether the chemical substance is a factor influencing the endocrine system as an endocrine disruptor or a factor influencing the endocrine system as stress.
机译:本发明提供了一种用于确定影响生物体中内分泌系统的化学物质的因子的方法,其中该方法包括(1)一种步骤,其中基因的表达量用作标记和/或量的基因 用作从未与化学物质与化学物质接触的受试者收集的样品中的内源性代谢物,并测量与化学物质接触的受试者进行,并进行(2)载体的表达量和/ 随后分析了在步骤(1)中测量的内源代谢物的量,并确定化学物质是否是影响内分泌系统作为内分泌破坏器的因素或影响内分泌系统作为应力的因素。

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