Composition for prevention and treatment of muscular disorder or improvement of muscular functions comprising gentiana extract or gentiopicroside

摘要

The present invention relates to a composition for preventing and treating or improving muscle function containing gentiana extract or gentiopicroside. The composition according to the present invention increases the activity of mTOR involved in muscle protein synthesis, and reduces the mRNA expression levels of MuRF1 and atrogin-1, thereby causing atony, muscular atrophy, muscular dystrophy, It can be usefully used for preventing, treating or improving various muscle diseases such as muscle degeneration, myasthenia gravis, cachexia and sarcopenia.