Methods for treating non tuberculous mycobacterial pulmonary infections

摘要

Problem to be solved herein is a method for treating a pulmonary infection, e.g., a non tuberculous mycobacterial pulmonary infection in a patient requiring it during at least one therapeutic period.The method includes administering a pharmaceutical composition to a patient's lungs including liposome complexed aminoglycosides, including lipid components containing electrically neutral lipids and aminoglycosides.The administration provides an aerosolized pharmaceutical composition comprising a mixture of free aminoglycosides and liposome complexed aminoglycosides by aerating the pharmaceutical composition Administering the aerosolized pharmaceutical composition to the patient's lungs through a nebulizer.The methods provided herein may result in changes from the baseline at a semi quantitative scale of a mycobacterial culture on a treated patient and / or negative conversion of the NTM culture during or during a administration period.No selection