Method and composition for treating Hunter syndrome by side ventricle administration

摘要

In one aspect, the present invention can be administered to the lateral ventricle once per week to treat the Hunter syndrome of the subject, isononic acid 2-sulfatase beta (IDS) - β） The present invention relates to a pharmaceutical composition comprising.Compared with a single dose of active doses of the same dose, the present invention demonstrates excellent effects in treatment of Hunter syndrome by repeated repeated administration over a long period of time, and the following effects are unanticipable from single dose results: treatment or recovery of damaged brain structures; And substantial treatment or improvement of brain function, particularly improvement of memory and learning.No selection