METHODS AND SYSTEMS FOR RECONSTRUCTING A 3D ANATOMICAL STRUCTURE UNDERGOING NON-RIGID MOTION

摘要

There are described methods and systems for reconstructing a 3D anatomical structure undergoing non-rigid motion. The method comprises obtaining a 3D reference volume of the anatomical structure of the body, the reference volume corresponding to the anatomical structure at a reference phase of a respiratory cycle; acquiring 2D images of the anatomical structure at m prior times Tin = {t-m,..., t-2, t-1}; estimating a set of deformations of the 3D reference volume at times n future Tout = {t, t+1,..., t+n} from a previously learned probability distribution conditioned on partial observations and anatomical information; applying a spatial transformation to the 3D reference volume based on the set of deformations; and displaying the reference volume post-spatial transformation as a motion-compensated anatomical structure for each time step i ϵ Tout.