首页>
外国专利>
MULTI-OMIC ANALYSIS IN MONODISPERSE DROPLETS
MULTI-OMIC ANALYSIS IN MONODISPERSE DROPLETS
展开▼
机译:单分散液滴中的多OMIC分析
展开▼
页面导航
摘要
著录项
相似文献
摘要
This disclosure provides methods and systems for single-cell, multi-omic analysis of target cells without microfluidic devices. The disclosed methods involve the use of template particles to template the formation of monodisperse droplets to generally capture a single target cell from a population of cells in an encapsulation, derive a plurality of distinct mRNA molecules from the single target cell, and quantify the distinct mRNA molecules to generate an expression profile. Nucleic-acid-tagged antibody conjugates are used for simultaneous proteomic analysis along with the gene expression profiling.
展开▼