RAPID EXTRACELLULAR ANTIBODY PROFILING (REAP) FOR THE DISCOVERY AND USE OF SAID ANTIBODIES

摘要

The present invention relates to methods for a sensitive and high-throughput detection of various antibodies and targets thereof. For example, in one aspect, methods of the present invention can successfully detect autoantibodies against extracellular and secreted proteins. In various embodiments, the present invention provides methods of diagnosing, assessing prognosis, preventing, and treating diseases or disorders associated with antibodies or targets thereof detected via the high-throughput detection methods of the present invention.