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PROCESS FOR PRODUCING COMPOUNDS OF INTEREST FROM AT LEAST ONE MINERALIZED CONNECTIVE TISSUE, AND COMPOUNDS OF INTEREST DERIVED FROM THIS PRODUCTION PROCESS

机译:制备来自至少一种矿化结缔组织的感兴趣化合物的方法,以及衍生自该生产过程的感兴趣的化合物

摘要

The present invention relates to a process for producing compounds of interest from at least one mineralized connective tissue, and to said compounds of interest comprising at least collagen. The production process comprises a step of solid/liquid extraction in which said at least one mineralized connective tissue is mixed with an eluent suitable for extracting said compounds of interest from said at least one mineralized connective tissue to said eluent. This extraction step comprises successive operations of adjusting the pH of said eluent, separated by a time interval; which operations of adjusting the pH each comprise an addition of an acid to the mineralized connective tissue/eluent mixture in order to reduce the pH of said eluent to achieve a pH value of less than or equal to 5.5, preferably less than or equal to 4, preferably ranging from 2 to 4.
机译:本发明涉及从至少一种矿化结缔组织中制备感兴趣的化合物的方法,并包含至少胶原蛋白的所述感兴趣的化合物。 制备方法包括固体/液体提取的步骤,其中所述至少一种矿化结缔组织与适于从所述至少一种矿化结缔组织提取到所述洗脱液的所述感兴趣的化合物的洗脱液中混合。 该提取步骤包括调节所述洗脱液的pH的连续操作,通过时间间隔分离; 调节pH的调节的操作包括向矿化结缔组织/洗脱液混合物中加入酸,以减少所述洗脱液的pH以达到小于或等于5.5,优选小于或等于4的pH值 ,优选地范围为2至4。

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