Complex comprising a ligand, a spacer, a peptide linker and a biological molecule

摘要

[Problem] To provide a complex comprising a ligand, a spacer, and a peptide linker useful for in vivo diagnostics and radiotherapy using an anti-human MUC1 antibody Fab fragment whose binding activity is not attenuated even by labeling with a metal or a fluorescent dye. [Solutions] A complex comprising a biomolecule containing 3arm DOTA, a specific spacer, a specific peptide linker, and an anti-human MUC1 antibody Fab fragment does not reduce binding activity even by labeling with a metal or a fluorescent dye, and a diagnostic composition and / Or it can be used as a pharmaceutical composition.