METHOD FOR PREDICTING LATENT NOCTURNAL INEFFECTIVENESS OF ANTIHYPERTENSIVE THERAPY IN THE SUMMER PERIOD

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine, namely to cardiology, therapy and neurology, and can be used in predicting latent nocturnal ineffectiveness of antihypertensive therapy in the summer period in patients with the target clinical and ambulatory blood pressure (BP) achieved on antihypertensive therapy outside the summer period. For this purpose, at a medical appointment outside the summer period, the heart rate (HR) in orthostasis is measured 1 minute after the patient stands up from a sitting position, their daily living physical activity and the fact of past and current smoking are considered, followed by calculating the coefficient of nocturnal ineffectiveness of treatment of arterial hypertension (AH) in the summer (CNET of AHS) by the original mathematical formula: CNET of AHS=6.214+2.973*S(0/1)-1.867*PA(0/1)-0.081*HRort., wherein: S is the fact of smoking, PA is the level of physical activity, HRort. is the heart rate in orthostasis. S is therein estimated as 1 if the patient smokes or used to smoke in the past, as 0 if the patient does not smoke and has not smoked in the past. PA is estimated as 1 if the level of physical activity in the patient corresponds to moderate or intensive physical activity, and as 0 if the physical activity is low. HRort. is estimated as the actual heart rate per 1 minute, measured in the standing position of the patient 1 minute after standing up from the sitting position. If the value of the CNET of AHS is less than or equal to -0.5, the absence of nocturnal rise in the BP and latent ineffectiveness of treatment of AH in the summer period is predicted in the patient. If the value of the CNET of AHS is greater than -0.5, a nocturnal rise in the BP, a nocturnal latent ineffectiveness of treatment of AH in the summer period are predicted in the patient, and ambulatory blood pressure monitoring (ABPM) is assigned.;EFFECT: method provides a differentiated approach to assigning ABPM to such patients, as well as preliminary intensification of drug-free preventive measures.;1 cl, 3 ex