Methods and apparatus to control communications of endpoints in an industrial enterprise system based on integrity are disclosed. An example apparatus includes an integrity measurement comparator to compare an integrity measurement to a reference value. The integrity measurement is generated by an endpoint in a network of an industrial enterprise system based on a state of the endpoint. The reference value corresponds to a trusted state of the endpoint. The example apparatus also includes an authorization controller to enable communications access for the endpoint on the network based on the comparison of the integrity measurement to the reference value.
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