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PHARMACEUTICAL COMPOSITION FOR LOWERING BLOOD CHOLESTEROL, PREVENTING OR TREATING CARDIOVASCULAR DISEASES AND REDUCING INFLAMMATION
PHARMACEUTICAL COMPOSITION FOR LOWERING BLOOD CHOLESTEROL, PREVENTING OR TREATING CARDIOVASCULAR DISEASES AND REDUCING INFLAMMATION
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机译:用于降低血液胆固醇,预防或治疗心血管疾病并减少炎症的药物组合物
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摘要
The present invention relates to a pharmaceutical composition and the like for lowering blood cholesterol, preventing or treating cardiovascular diseases and reducing inflammation, containing, as an active ingredient, an inhibitor of binding between CAP1 and PCSK9, an inhibitor of binding between CAP1 and resistin, or a CAP1 gene expression inhibitor. The present invention can lower the level of blood LDL-cholesterol by inhibiting the binding of CAP1 and PCSK9, the binding of CAP1 and resistin or the expression of a CAP1 gene. Therefore, the present invention can be effectively used as a pharmaceutical composition and the like for treating abnormal blood cholesterol levels and various cardiovascular diseases caused thereby, such as dyslipidemia, stroke, arteriosclerosis, and the like, and for inhibiting inflammation.
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