MICROORGANISMS FOR PRODUCING O-SUCCINYL HOMOSERINE AND A METHOD OF PRODUCING O-SUCCINYL HOMOSERINE USING SAID MICROORGANISMS

摘要

FIELD: biotechnology.;SUBSTANCE: invention provides a method of producing methionine, involving a) culturing a microorganism in a medium; b) obtaining O-succinyl homoserine from a microorganism or medium; c) converting O-succinyl homoserine to methionine using cystathionine-gamma synthase or O-succinyl homoserine sulfhydrylase, where microorganism is Escherichia sp. microorganism, producing O-succinyl homoserine, expressing polypeptide, possessing resistance to methionine inhibition by feedback principle and homoserine succinyl transferase activity, where polypeptide has amino acid sequence SEQ ID NO: 1.;EFFECT: invention enables to obtain methionine with high efficiency.;4 cl, 2 tbl, 4 ex