首页> 外国专利> 2,6-DISUBSTITUTED 1,2,4-TRIAZINE-3,5-DIONE COMPOUND, AND PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF

2,6-DISUBSTITUTED 1,2,4-TRIAZINE-3,5-DIONE COMPOUND, AND PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF

机译:2,6-二取代的1,2,4-三嗪-3,5-二酮化合物,以及其制备方法及其应用

摘要

The present invention provides a 2,6-disubstituted 1,2,4-triazine-3,5-dione compound having a structure represented by Formula I, or a pharmaceutically acceptable salt thereof. The above triazone derivative has a novel structure and exhibits an excellent THRβ agonistic effect, and can therefore play a role as a drug for the treatment and/or prophylaxis of a thyroid hormone receptor-related disease.
机译:本发明提供了一种具有由式I表示的结构的2,6-二取代的1,2,4-三嗪-3,5-二酮化合物,或其药学上可接受的盐。 上述三塞酮衍生物具有新颖的结构,并且表现出优异的三倍体效应,因此可以发挥作用作为治疗和/或预防甲状腺激素受体相关疾病的药物的作用。

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