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PREPARATION AND USE OF IMMUNOSTIMULATORY COUPLING COMPLEX WHICH IS DELIVERED AND ACTIVATED IN TARGETED MANNER

机译:制备和使用免疫刺激偶联复合物,其以目标方式递送和活化

摘要

Provided are the preparation and use of an immunostimulatory coupling complex which is delivered and activated in a targeted manner. Specifically, provided are a compound as represented by Formula MI-S-C-A which is used as a connecting arm, and a pharmaceutical compound as represented by Formula MI-S-C-A-D, to which a dug is connected. The pharmaceutical compound has the advantages of improved water solubility, reduced cytotoxicity, and enhanced drug activity.
机译:提供的是制备和使用免疫刺激偶联复合物,其以目标方式递送和活化。 具体地,提供的是由式Mi-S-C-A表示的化合物,其用作连接臂,以及由式Mi-S-C-A-D表示的药物化合物,挖掘连接的式Mi-S-C-A-D。 药物化合物具有改善水溶性,降低细胞毒性和增强的药物活性的优点。

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