APPLICATION OF NIEMANN-PICK C1 PROTEIN IN DIAGNOSIS AND TREATMENT OF CANCER

摘要

A use of Niemann-Pick C1 (NPC1) protein and a substance that inhibits NPC1 gene expression and/or protein activity, which is selected from at least one of the following (a)-(h): (a) for the preparation of kits for diagnosing cancer; (b) for the preparation of kits for predicting the prognosis of cancer; (c) for the preparation of kits for performing a companion diagnostic for cancer treatment; (d) for the preparation of drugs for the prevention and/or treatment of cancer; (e) for the preparation of drugs for the prevention and/or treatment of cancer spread and metastasis; (f) for the preparation of drugs for promoting apoptosis of cancer cells; (g) for the preparation of drugs for inhibiting cancer cells from developing into cancer; (h) for the preparation of drugs for inhibiting in vitro proliferation and growth of cancer cells.