USE OF MCM5 AS A MARKER FOR GYNAECOLOGICAL CANCERS

摘要

The present invention relates to methods for detecting the presence or absence of a gynaecological cancer in a subject, the method (a) comprising obtaining a non-invasive sample isolated from the subject; and (b) treating the non-invasive sample to release at least one biomarker from cells in the non-invasive sample. The present invention also relates to lysis buffers, monoclonal antibodies, and kits that can be used in such methods. The present invention also relates to a method for diagnosing a subject as having a gynaecological cancer or a benign gynaecological condition. The present invention also relates to a method for distinguishing between a non-invasive sample associated with a gynaecological cancer and a non-invasive sample associated with a benign gynaecological cancer. The present invention further relates to a method for stratifying a subject into one of two treatment groups.