METHOD FOR DETERMINING THE RISK OF TRANSFORMATION OF A STATIONARY CHOROIDAL NEVUS INTO A PROGRESSIVE NEVUS

摘要

FIELD: biotechnology.;SUBSTANCE: invention relates to biotechnology, namely to ophthalmic oncology, and is intended for determining the risk of transformation of a stationary choroidal nevus into a progressive nevus. Genomic ctDNA with mutations of the GNAQ/GNA11 genes is determined in peripheral blood plasma using polymerase chain reaction (PCR) in real time. If mutations are present in exons 4 and/or 5, the risk of transformation is determined.;EFFECT: provides a possibility to select an appropriate treatment strategy as a result of screening patients with a high risk of transformation of a stationary nevus into a progressive choroidal nevus.;1 cl, 1 tbl, 4 ex