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SPECIFIC TO MRS. CONNECTING MONOCLONEL ANTICIPERS
SPECIFIC TO MRS. CONNECTING MONOCLONEL ANTICIPERS
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机译:特定于太太。 连接Monoclonel Italipers.
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摘要
The present invention relates to an anti-MRS monoclonal antibody and, more specifically, to an antibody or a fragment thereof characterized by specifically binding to a fragment represented by amino acid 861-900 of a human-derived methionyl-tRNA synthetase (MRS) protein set forth in SEQ ID NO:1, a method for producing the same, and a composition for diagnosing cancer comprising the same. The antibody or the fragment thereof of the present invention specifically binds to the human-derived MRS, and has no cross-reactivity with other proteins comprising the same ARS family. Therefore, as MRS detection is possible, the antibody or a fragment thereof can be effectively used for diagnosing MRS-related cancer.
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机译:抗MRS单克隆抗体和更具体地,涉及一种抗体或其片段,其特征在于特异性结合人衍生的甲硫醇-TRNA合成酶(MRS)蛋白代表的氨基酸861-900代表的片段 在SEQ ID NO:1中阐述,一种制备方法,以及用于诊断包含相同癌症的组合物。 本发明的抗体或其片段特异性结合人衍生的MRS,并且没有与包含相同ARS系列的其他蛋白质的交叉反应性。 因此,随着MRS检测是可能的,抗体或其片段可以有效地用于诊断MRS相关的癌症。
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