An ocular cranial nerve monitoring system (OCNMS) that provides continuous measurement of pupillary reactivity in the eye. The system features a sensor component that produces a stimulating light and a recording light and records reflected recording light so as to calculate pupillary diameter and response to stimulation as measured by latency, velocity, and/or amplitude. This system of the present invention may be used for indirect assessment of the 2nd and 3rd cranial nerve (CN 2, CN3) pathways and/or intracranial pressure in patients and may be used intraoperatively. The data obtained from this system may allow for immediate corrective actions, which may help prevent permanent deficits and improve patient safety and surgical outcomes. In some instances, the system may help avoid unnecessary or invasive procedures (e.g., catheters inserted for intracranial pressure monitoring).
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