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DELIVERY OF LOW SURFACE TENSION COMPOSITIONS TO THE PULMONARY SYSTEM VIA ELECTRONIC BREATH ACTUATED DROPLET DELIVERY DEVICE
DELIVERY OF LOW SURFACE TENSION COMPOSITIONS TO THE PULMONARY SYSTEM VIA ELECTRONIC BREATH ACTUATED DROPLET DELIVERY DEVICE
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机译:通过电子呼吸驱动液滴输送装置向肺系统输送低表面张力组合物
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摘要
A droplet delivery device and related methods for delivering a low surface tension composition as a stream of droplets to a subject for pulmonary use is disclosed. The droplet delivery device includes a housing, a reservoir, an ejector mechanism, and at least one differential pressure sensor. The droplet delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The ejector mechanism includes a piezoelectric actuator and an aperture plate, the aperture plate having a plurality of openings formed through its thickness, and one or more surfaces configured to provide a desired surface contact angle, and the piezoelectric actuator operable to oscillate the aperture plate at a frequency to thereby generate the ejected stream of droplets.
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