.LIPOSOME WITH ENHANCED SKIN PERMEATION AND MANUFACTURING METHOD THEREOF

摘要

The present invention relates to a liposome comprising an aqueous phase component and an oil phase component, wherein the aqueous phase component includes a water-soluble active ingredient and a charge stabilizer, the oil phase component includes a membrane softener, and the charge stabilizer comprises a hydrophilic-lipophilic-hydrophilic group It is a tri-block copolymer consisting of a block, and the membrane softener is an amphoteric polymer consisting of a block of a hydrophilic group-lipophilic group, and is characterized in that it has a Hydrophilic Lipophilic Balance (HLB) of 10 or more.