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COMPOSITIONS AND METHODS FOR TREATING BIOFILMS, INFECTIONS AND PERIODONTITIS

机译:治疗生物膜,感染和牙周炎的组合物和方法

摘要

In alternative embodiments, provided are compositions, including products of manufacture, pharmaceutical compositions and kits, and methods, for treating, ameliorating, preventing or reducing the growth of, a biofilm, such as a biofilm in an oral environment, such as a biofilm growing on or adherent to a tooth an implant, or an oral prosthetic, or microbial colonies found in biofilms. In alternative embodiments, provided are compositions, including products of manufacture and kits, and methods, for treating, ameliorating, preventing or reducing the severity of an infection. In alternative embodiments, antibacterial and therapeutic formulations as provided and used herein are derived or isolated from Streptococcus sanguinis and/or Staphylococcus epidermidis organisms or cultures.
机译:在替代实施方案中,提供的是组合物,包括制造,药物组合物和试剂盒的产物,以及用于治疗,改善,预防或降低生物膜的生长,例如生物膜在口腔环境中的生长,例如生物膜生长在植入物或在生物膜中发现的口腔假肢或口腔假体或微生物菌落的牙齿上或粘附。在替代实施方案中,提供的是组合物,包括制造和试剂盒的产物,以及用于治疗,改善,预防或降低感染的严重程度的方法。在替代实施方案中,本文提供和使用的抗菌和治疗制剂是从链球菌的衍生或分离出来的,并且/或葡萄球菌Epidermidis 生物体或培养物。

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