PLASMONICS SENSING NANOPLATFORMS FOR HUMAN STEM CELL APPLICATIONS AND METHODS THEREOF

摘要

A method of monitoring viability of stem cell-derived cells used in stem cell therapy comprises introducing one or more stem cell-derived cells to a cell culture media, introducing one or more nanoprobes to the cell culture media, whereby the one or more stem cell-derived cells are transfected with the one or more nanoprobes, and detecting an optical signal from the one or more nanoprobes after transfection. The method may further comprise introducing the one or more transfected stem cell- derived cells to a subject and detecting the optical signal from the one or more nanoprobes in vivo. The one or more stem cell-derived cells may include a stem cell.