Determination of testosterone in multiplexed patient samples by mass spectrometry

摘要

A method of high throughput determination of testosterone, which utilizes at least two different derivatizers of different masses, is provided herein.In another aspect,Each of a plurality of human samples is attached to a different derivatization agentGenerating individually derivatized testosterone in each of a plurality of samples;Forming multiple samples by combining multiple samplesAnd by mass spectrometryBy quantifying the amount of testosterone in each sampleIn a single mass spectrometry essayIn each of a plurality of human samplesHow to determine the amount of testosterone isProvided herein.Diagram