An extended reality-based system for dynamic assessment of upper extremity impairments is disclosed. A virtual environment is provided to a user. A target path is received. A sensory stimulus is presented to the user. Three-dimensional position information is determined for one or more body part defining a recorded path. A plurality of motion parameters corresponding to a user response to the stimulus are determined by: comparing the recorded path to the target path, determining a smoothness metric of the recorded path, determining starting coordinates and ending coordinates of the path, determining a first time period from presentation of the sensory stimulus to when motion of the one or more body part begins, and determining a second time period for motion between the starting coordinates and the ending coordinates. At least one index indicative of upper extremity impairment from the plurality of motion parameters.
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