首页> 外国专利> BARCODED WELLS FOR SPATIAL MAPPING OF SINGLE CELLS THROUGH SEQUENCING

BARCODED WELLS FOR SPATIAL MAPPING OF SINGLE CELLS THROUGH SEQUENCING

机译:通过测序的单细胞空间映射条形码孔

摘要

Disclosed herein include systems, methods, compositions, and kits for methods of assigning sequencing data to partitions. There are provided, in some embodiments, methods of associating sequencing data and phenotypic data of single cells. There are provided, in some embodiments, methods of reducing noise in sequencing data. Disclosed herein include partition indexing oligonucleotides comprising a partition indexing sequence. The partition indexing oligonucleotides can be associated with partitions. Partition indexing oligonucleotides situated within the same partition can comprise the same partition indexing sequence. Partition indexing oligonucleotides situated within different partitions comprise different partition indexing sequences.
机译:本文公开了包括将测序数据分配给分区的方法的系统,方法,组合物和套件。在一些实施方案中提供了将测序数据和单细胞表型数据相关联的方法。在一些实施例中提供了在序列数据中降低噪声的方法。本文公开了包括含有分配索引序列的分配索引寡核苷酸。分区分度寡核苷酸可以与分区相关。位于相同分区内的分区分度寡核苷酸可包括相同的分区索引序列。位于不同分区内的分区分度寡核苷酸包括不同的分配索引序列。

著录项

  • 公开/公告号US2021230583A1

    专利类型

  • 公开/公告日2021-07-29

    原文格式PDF

  • 申请/专利权人 BECTON DICKINSON AND COMPANY;

    申请/专利号US202117161558

  • 发明设计人 GRETCHEN LAM;

    申请日2021-01-28

  • 分类号C12N15/10;C12Q1/6874;

  • 国家 US

  • 入库时间 2022-08-24 20:14:20

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