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MULTI-CENTER SYNERGETIC CANCER PROGNOSIS PREDICTION SYSTEM BASED ON MULTI-SOURCE MIGRATION LEARNING

机译:基于多源迁移学习的多中心协同癌预测预测系统

摘要

Provided is a multi-center synergetic cancer prognosis prediction system based on multi-source migration learning. The system comprises a model parameter setting module, a data screening module and a multi-source migration learning module, wherein the model parameter setting module is used for setting cancer prognosis prediction model parameters; the data screening module is arranged at a clinical center, and a management center transmits the set model parameters to each clinical center, such that each clinical center queries sample features and prognosis index data from a local database according to the model parameters, so as to preprocess the data; and the multi-source migration learning module comprises a source model training unit, a migration weight calculation unit, and a target model calculation unit. The use of multi-source migration learning to solve the problem of heterogeneous data between a source center and a target center and the problem of insufficient label data at the target center makes it possible to construct a more accurate prediction model taking the heterogeneous data at a plurality of centers into consideration. Meanwhile, complementation and sharing of original data from all institutions during a model training process are realized, thereby avoiding breaching the privacy of patients.
机译:提供基于多源迁移学习的多中心协同癌预测预测系统。该系统包括模型参数设置模块,数据筛选模块和多源迁移学习模块,其中模型参数设置模块用于设定癌症预测预测模型参数;数据筛选模块布置在临床中心,管理中心向每个临床中心发送设定的模型参数,使得每个临床中心根据模型参数查询来自本地数据库的样本特征和预后指数数据,以便预处理数据;并且多源迁移学习模块包括源模型训练单元,迁移权重计算单元和目标模型计算单元。使用多源迁移学习来解决源中心和目标中心之间的异构数据问题以及目标中心的标签数据不足的问题使得可以构建更准确的预测模型,从而占据异构数据多个中心考虑。同时,实现了在模型培训过程中的所有机构的互补和分享原始数据,从而避免违反患者的隐私。

著录项

  • 公开/公告号WO2021143781A1

    专利类型

  • 公开/公告日2021-07-22

    原文格式PDF

  • 申请/专利权人 ZHEJIANG LAB;

    申请/专利号WO2021CN71827

  • 发明设计人 LI JINGSONG;TIAN YU;CHEN WEIGUO;MA JING;

    申请日2021-01-14

  • 分类号G16H50/70;

  • 国家 CN

  • 入库时间 2022-08-24 20:09:31

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