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Protein sequence optimization method using amino acid co-evolutionary information
Protein sequence optimization method using amino acid co-evolutionary information
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机译:蛋白质序列优化方法使用氨基酸共同进化信息
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摘要
The present invention relates to a method for designing a protein-optimized mutant sequence using amino acid co-evolution information. Specifically, it uses amino acid co-evolution information and protein tertiary structure information to maintain the original function of the protein while improving the expression level, water solubility, stability and functionality. It relates to a method for searching for a protein having a mutant sequence.
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